FAQ

Select a category for your question:

Services
Can you perform an assay?

We use a number of analytical techniques in-house to characterize our products including native and SDS-PAGE followed by a variety of staining methods, , protein concentration, endotoxin determination, KDO and phosphate analysis, a variety of binding assays, Western blot, ELISA, HPLC,  thin layer chromatography, cell cytotoxicity assays, cytokine assays, fluorescent and colorimetric enzyme assays.  For selected products, we have electrospray mass spectrometry (ESI-MS) performed to determine molecular weight.

Through contract services, we offer a highly sensitive assay to detect low levels of botulinum neurotoxin type A (BoNT/A) in complex matrices and diluted plasma.  We also have a sensitive and specific assay for detection of anthrax lethal factor (LF) in plasma.

Orders
Are there additional fees for dangerous goods?

A $50 dangerous goods fee is added to each dangerous goods shipment in addition to the carrier shipping fee.

What is the procedure for purchasing a Select Agent and Toxin?

Our price list indicates which items are Select Agents and Toxins.  Link to the Federal Select Agent Program:  http://www.selectagents.gov/  The Federal Select Agent Program is jointly regulated by the Centers for Disease Control and Prevention/Division of Select Agents and Toxins (CDC DSAT) and the Animal and Plant Health Inspection Services/Agriculture Select Agent Services (APHIS AgSAS).  Although excluded amounts can be purchased outside of this program, certain purchases require the user to register with the Federal Select Agent Program and to obtain permission for each shipment.

What are my shipping carrier options?

A majority of List Labs products ship via FedEx both domestically and internationally. Select Agents & Toxins/Dangerous Goods are shipped via UPS domestically and via World Courier internationally.

Do I have to insure my package?

We insure packages through the shipping carrier. If your institution has insurance you may request for the shipment not to be insured. However, our FOB (free on board) terms are Campbell, California, making the recipient liable for the package once it is in the hands of the carrier after it leaves our facility.

Do you offer discounts for volume purchases?

Yes, we have a generous volume discount program, outlined on our U.S. Orders page, starting with as few as 10 vials or $2500. Bulk orders also qualify. You can submit a bulk request here.

New Customers
Do I have to complete the entire form (new customer application)?

If payment will be by credit card or payment in advance you do not have to complete the credit section.  

Do I need a new customer application if I purchase online?

An account needs to be established for each institution and to do this a new customer application is required for all customers, regardless of purchase method. 

Product Information
What are the differences between reagent grade, quality documented, and cGMP grades?

Comparison of Product Grades

 

Reagent Grade

Quality Documented

cGMP

 QUALITY

 Quality system

 Quality control & release of materials documented per GMP  regulations

 All activities are approved and reviewed by the Quality  Assurance group

X

 

 

X

X

X

 

X

X

X

 

X

 Deviation and change control

X

X

X

 Manufacturing procedures are documented & approved

 Requirements of 21CFR211.186 and 188, Q7A are met

 Master Production & Control Records prepared per 21CFR211.186

 Batch Production & Control Records prepared & issued  per 21CFR211.188

X

X

X

X

 

X

X

X

X

 

X

 QC tested for identity and purity

 Additional analyses may be performed

 Assay validation or qualification

X

X

X

X

X

X

 Raw material traceability, lot numbers recorded

 Certificates of Analysis are collected and reviewed

 Visual inspection performed, if appropriate, the material released for  use

 Raw material testing

 Prior to release, materials are held in quarantine

 System is in place for rejecting materials

 Chemical grade of raw materials

X

 

 

 

 

 

 

Not specified

X

X

X

 

 

X

X

Not specified; usually compendial

X

X

X

 

X

X

X

Com-pendial

 FACILITIES & EQUIPMENT

 Facility validation

 

X

X

 Equipment is either calibrated traceable to NIST standards  or standardized with qualified standards

X

X

X

 Environmental monitoring

 

Quarterly

Weekly

 Equipment usage and cleaning

X

X

X

 Validation and qualification of equipment  (IQ, OQ, PQ)

 

 

X

 Equipment cleaning validation or dedicated equipment

 

 

X

 MANUFACTURING

 Personnel training

X

X

X

 Significant steps in manufacturing are verified by a second person

 

X

X

 Manufactured in  environmentally controlled area for particle control

On request

X

X

 Process validation

 

 

X

Can you reconstitute a lyophilized product for me?

If your institution would prefer that you not work with lyophilized toxins, we can reconstitute certain products for you.  A nominal fee will apply, if your purchase is just a single vial.  After reconstitution, the item ships on Blue Ice, and this increases transportation and box fees.

I see that you offer three different versions of pertussis toxin, which one should I purchase

We offer three different formulations.  Product #179A/B is provided frozen in a glycerol formulation.  This product is already in solution and adds the convenience of being readily available for each use.  However, shipping on blue ice is required, and it is not available internationally.  Product #180 is provided lyophilized in sodium phosphate buffer.  It is stable when shipped at ambient temperature and suitable for most applications.  Product #181 is provided lyophilized without a buffer, which allows you reconstitute the pertussis toxin in the buffer of your choice.

What is LD50 and is it available for all products?

Lethal dose 50% (LD50) is described in the following link:  http://www.ccohs.ca/oshanswers/chemicals/ld50.html.  We do not perform this assay, and LD50 is not provided for our products.  If it is required, we will subcontract this work.

Liquid or lyophilized? Why are some items offered in a liquid form?

When it is feasible, we lyophilize our products to enhance the stability.  Some of our products, though, lose activity upon freezing and are therefore not lyophilized or frozen.  Our liquid products are shipped on dry ice or Blue Ice, which require prompt transportation and delivery.  Storage conditions after receipt are provided on the Certificate of Analysis enclosed with each item that is purchased.

Stability – how long will the product be active after reconstitution?

Most of our products are offered as a lyophilized powder which allows the item to ship at room temperature.  Stability varies from product to product.  The Certificate of Analysis reports stability data after reconstitution, if known.  However, the product may have multiple applications, and stability varies for different applications.

Are your products for human use?

Our products are for research purposes only and are not to be used in humans or as diagnostic agents.  We do have capabilities to provide GLP or GMP products utilizing our contract manufacturing capabilities.

What is the difference between a new customer application and an online account?

An online account is established for customers who wish to place their orders via our online ordering process. A new customer application is completed when the institution is placing an order at List Labs for the first time.

What are your shipping policies?

We provide same day shipping for most orders received before noon Pacific Standard Time. Orders arriving after noon ship the following business day.

Products requiring cold packaging ship Monday, Tuesday or Wednesday only due to the temperature requirements for liquids. They must be shipped via standard overnight or priority overnight. 

For room temperature domestic shipments you may choose Standard Overnight (delivery to most locations by end of the next business day), Priority Overnight (delivery to most locations by 10:30 a.m. the next morning), or Economy Service which is a two day delivery.  

Packages going to international destinations are shipped Federal Express International Priority. Some exceptions apply.

We prepay shipping fees and add the freight charges to your invoice, unless you provide your carrier's account number when placing your order.

How long does it take to get the new customer application approved?

Generally, one to three business days.

Shipping
Can I schedule an automatic reorder of my products?

If you would like to set this up we would be happy to help you. Please speak to a customer service representative about standing purchase orders.

What information is shipped with the product?

A certificate of analysis is provided with each shipment. When it is a dangerous good that ships on a hazardous declaration an SDS also is included with the shipment.

Do you offer weekend delivery?

If you will be at your place of business on Saturday, arrangements can be made for a delivery on a Saturday. Please contact our customer service department about special needs like this.

Do you ship all products internationally?

Yes, however some products have additional requirements for international shipments.

Products shipped on Blue Ice or Dry Ice require a written statement from customers stating they agree to receive the products in the condition that they arrive. A simple line on a purchase order with the statement, “I agree to receive products shipped on ice in the condition they arrive.” will suffice.

Select Agents & Toxins can only be carried internationally via World Courier.

Miscellaneous
Do you offer custom sizes?

We can offer custom sizes. Some products allow us to do this easily and can be provided cost effectively.  The larger the quantity desired, the more cost effective the project will be.

Can I return a product?

Due to our commitment to quality and the nature of our products, we are unable to accept returns.

My company is outside the US. Can I buy from you direct?

Some relationships with distributors are exclusive, while others are not. Please contact our customer service department with your specific location or review the distributor page.

Are there additional requirements for shipment of select agents?

Please see our section on controlled substances.