List Biological Laboratories, Inc. is dedicated to providing research reagents to advance the understanding of disease and to further the development of vaccines, therapeutics and diagnostics. At the same time we are committed to exploiting the full potential of bacteria, their toxins, virulence factors and enzymes in treating infectious disease, developing cancer therapies and detecting potential threats. We welcome inquiries in these and other related areas.
List Labs has extensive experience producing bulk Drug Substances (DS) and Active Pharmaceutical Ingredients (API) as defined by Q7A Good Manufacturing Practice Guidance and current 21 CFR Parts 211, as well as facility design and technology transfer.
List Labs has developed a process to make highly purified lipopolysaccharide from E. coli O113. LPS or Lipid A can be custom produced under cGMP guidelines in our laboratory for your clinical research program. We have a limited supply of cGMP LPS available for sale directly. This can be a dramatic cost savings over custom production.
We cultivate many bacterial strains to produce our reagents. A variety of bacteria, themselves, are currently of great interest because of their therapeutic potential. Do you have a strain which you would like produced for clinical trials?
Cholera Toxin Adjuvant
Cholera Toxin has been demonstrated to be effective as a vaccine adjuvant and transdermal delivery vehicle. Our Cholera Toxin has been used for clinical trials, and we are capable of making this or another toxin cGMP for your clinical study.
We have developed, qualified and can perform for you, sensitive assays to detect Botulinum Toxin Type A in a complex matrix. Additionally, we have a bifunctional assay for Botulinum Type A which measures SV2c receptor binding and enzymatic activity.