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BORDETELLA PERTUSSIS LIPOPOLYSACCHARIDE (LPS)
LPS extracted from Bordetella pertussis is different in structure when compared with LPS from many species such as E. coli and S. minnesota. A major difference in this Bordetella endotoxin lies in the absence of an O polysaccharide or O antigen chain which, when present, forms the outermost domain of LPS. A non-repeating trisaccharide takes the place of the O antigen in some of the B. pertussis LPS population; another LPS congener lacks the trisaccharide. Two LPS congeners are resolved by electrophoresis; the slower migrating A band has the trisaccharide attached and the faster migrating B band does not. Due to the lack of an O antigen, B. pertussis LPS is referred to as rough LPS or as a lipooligosaccharide (LOS).
Other Bordetella pertussis virulence factors derived from native organisms and offered by List Labs, include Pertussis Toxin, Pertussis Toxin Subunits, Pertussis Toxin Mutant, native Adenylate Cyclase Antigen, Filamentous Hemagglutinin (FHA), Fimbriae 2/3 and Pertactin (69 kDa protein). Recombinant Adenylate Cyclase Toxin (ACT) is also available. More information about each of these products may be obtained through the links on the Bordetella Pertussis Virulence Factors.
List Labs sells LPS and Lipid A from several species of bacteria, which may be viewed through the link Lipopolysaccharides.
This product is also an adjuvant. For more information on adjuvants from List Labs, read our blog.